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199616-96-1

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199616-96-1 Usage

General Description

2-[4-(4-Bromo-phenyl)-piperazin-1-yl]-ethylamine is a chemical compound with a molecular formula C14H20BrN3. It is an organic amine containing a piperazine ring and a bromo-phenyl group. 2-[4-(4-BROMO-PHENYL)-PIPERAZIN-1-YL]-ETHYLAMINE is commonly used in medicinal chemistry as a building block for the synthesis of potential drug candidates, particularly antipsychotic and antidepressant agents. It is also known to exhibit affinity for various neuroreceptors, such as serotonin and dopamine receptors, making it of interest in the development of new pharmaceuticals for the treatment of psychiatric disorders. Additionally, this compound is a common reagent in chemical research and may have potential industrial applications in the production of fine chemicals and pharmaceuticals.

Check Digit Verification of cas no

The CAS Registry Mumber 199616-96-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,6,1 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 199616-96:
(8*1)+(7*9)+(6*9)+(5*6)+(4*1)+(3*6)+(2*9)+(1*6)=201
201 % 10 = 1
So 199616-96-1 is a valid CAS Registry Number.

199616-96-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[4-(4-bromophenyl)piperazin-1-yl]ethanamine

1.2 Other means of identification

Product number -
Other names 2-[4-(4-bromophenyl)piperazin-1-yl]-ethylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:199616-96-1 SDS

199616-96-1Upstream product

199616-96-1Downstream Products

199616-96-1Relevant articles and documents

Benzyl Phenylsemicarbazides: A Chemistry-Driven Approach Leading to G Protein-Biased Dopamine D4 Receptor Agonists with High Subtype Selectivity

Pirzer, Anna S.,Lasch, Roman,Friedrich, Heike,Hübner, Harald,Gmeiner, Peter,Heinrich, Markus R.

, p. 9658 - 9679 (2019/11/13)

Many subtype-selective dopamine receptor ligands developed for the D2-D4 family incorporate a 1-arylpiperazine-derived primary recognition motif, which is connected to a lipophilic moiety occupying an extended binding pocket (EBP) of the receptor via an aliphatic linker of variable lengths. The evaluation of a novel group of dopamine receptor ligands now showed that highly subtype-selective ligands [up to Ki(D4.4) = 0.25 nM, D2L/D4.4 = 320, D3/D4.4 = 710 for APH199 (17)] can be obtained by choosing a relatively large and conformationally flexible 1-benzyl-1-phenylsemicarbazide substructure to fill the EBP. The novel chemotype APH199 (17) was found to act as a full agonist at the D4 receptor showing significant bias toward G protein activation over β-arrestin recruitment in comparison to quinpirole.

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