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Givinostat (hydrochloride) is a chemical compound that belongs to the class of histone deacetylase (HDAC) inhibitors. It possesses the ability to block the activity of HDAC enzymes, which are involved in the regulation of gene expression and cellular processes. The inhibition of these enzymes by Givinostat can result in the reactivation of certain genes, potentially influencing various cellular functions. Its capacity to modulate gene expression and cellular processes positions Givinostat as a promising candidate for further research and potential medical applications.

199657-29-9

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199657-29-9 Usage

Uses

Used in Pharmaceutical Industry:
Givinostat (hydrochloride) is used as a therapeutic agent for its potential effects in treating a range of conditions. Its application is primarily due to its ability to inhibit HDAC enzymes, which can lead to the reactivation of genes and influence cellular functions.
Used in Cancer Treatment:
Givinostat (hydrochloride) is used as an anticancer agent, targeting the dysregulation of gene expression associated with cancer cells. By inhibiting HDAC enzymes, it can potentially suppress tumor growth and induce cell death in cancerous cells.
Used in Inflammatory and Autoimmune Diseases:
Givinostat (hydrochloride) is used as an anti-inflammatory and immunomodulatory agent, leveraging its HDAC inhibitory properties to regulate the expression of genes involved in inflammation and immune responses, potentially alleviating symptoms and disease progression in inflammatory and autoimmune conditions.
Used in Neurological Disorders:
Givinostat (hydrochloride) is used as a neuroprotective and neuroregenerative agent, with its HDAC inhibitory action potentially beneficial in the treatment of neurological disorders by influencing gene expression related to neuronal function and survival.

Check Digit Verification of cas no

The CAS Registry Mumber 199657-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,6,5 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 199657-29:
(8*1)+(7*9)+(6*9)+(5*6)+(4*5)+(3*7)+(2*2)+(1*9)=209
209 % 10 = 9
So 199657-29-9 is a valid CAS Registry Number.

199657-29-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl-[6-(4-hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride

1.2 Other means of identification

Product number -
Other names Givinostat (hydrochloride)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:199657-29-9 SDS

199657-29-9Downstream Products

199657-29-9Relevant academic research and scientific papers

MONOHYDRATE HYDROCHLORIDE OF THE 4-HYDROXYCARBAMOYL-PHENYL)-CARBAMIC ACID (6-DIETHYLAMINOMETHYL-NAPHTALEN-2-YL) ESTER

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Page 3-4, (2008/06/13)

A compound having formula (I) and a process for the preparation thereof are described.

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