199657-35-7Relevant academic research and scientific papers
Compounds with anti-inflammatory and immunosuppressive activities
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, (2008/06/13)
The present invention provides medicinal compounds that are characterized by a cyclic moiety (A) linked through a carboxamido group (more specifically, a carbamate group or a urea group) to another cyclic moiety (B) which is in turn linked to another, N-substituted carboxamido group. These compounds can be used an anti-inflammatory and immunosuppressive agents, as demonstrated by their inhibition of the production of IL-1β in vitro and TNFα in vivo.
