199680-91-6

Upstream product

• 199680-86-9 (E)-N-(6-Amino-1-methyl-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3,4-dimethoxy-phenyl)-acrylamide 
• 14737-89-4 3,4-dimethoxy-trans-cinnamic acid 
• 146830-75-3 5,6-diamino-3-prop-2-ynyl-1H,3H-pyrimidine-2,4-dione 
• 199680-81-4 (E)-N-(6-Amino-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3,4-dimethoxy-phenyl)-acrylamide 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of 3,7-dimethyl-1- propargylxanthine derivatives, A(2A)-selective adenosine receptor antagonists

A series of 8-substituted derivatives of 3,7-dimethyl-1- propargylxanthine (DMPX) was synthesized and investigated as A(2A) adenosine receptor antagonists. Different synthetic strategies for the preparation of DMPX derivatives and analogues were explored.