199731-27-6Relevant articles and documents
SYNTHESIS AND STEREOCHEMISTRY OF TROPANE 6-SPIRO-HYDANTOINS
Villacampa, Mercedes,Martinez, Manuel,Gonzalez-Trigo, Gregorio,Soellhuber, Monica M.
, p. 1885 - 1895 (2007/10/02)
The synthesis of several representatives of the previously unkown N-alkyl-nortropane-6-spirohydantoin ring system by Bucherer-Bergs reaction of 8-alkyl-8-azabicyclooctan-6-ones is described. 3-Oxo derivatives of the parent structure were also prepared.The stereochemical outcome of the Bucherer-Bergs reaction is discussed on the basis 1H-nmr and 13C-nmr data.