199801-75-7

Upstream product

• 162089-63-6 2-[(S)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-methyl-cyclohex-3-en-(Z)-ylidene]-ethanol 
• 349487-61-2 Acetic acid 2-[(2S,6S)-2-(tert-butyl-dimethyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-cyclohex-3-en-(E)-ylidene]-ethyl ester 
• 349487-60-1 Acetic acid 2-[(2S,6S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-methyl-cyclohex-3-en-(E)-ylidene]-ethyl ester 
• 349487-59-8 Acetic acid 2-[(S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-2-oxo-cyclohex-3-en-(E)-ylidene]-ethyl ester 
• 349487-58-7 Acetic acid 2-[(S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-cyclohex-3-en-(Z)-ylidene]-ethyl ester 
• 199801-73-5 2-[(2S,6S)-2-(tert-Butyl-dimethyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-cyclohex-3-en-(E)-ylidene]-ethanol 
• 199801-74-6 2,2,2-Trichloro-acetimidic acid 2-[(2S,6S)-2-(tert-butyl-dimethyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-cyclohex-3-en-(E)-ylidene]-ethyl ester 

Relevant academic research and scientific papers

Synthesis of a common key intermediate for (-)-tetrodotoxin and its analogs

A key intermediate for tetrodotoxin and its analogs such as (-)-5,11-dideoxytetrodotoxin was stereoselectively synthesized from a chiral starting material, levoglucosenone, via Diels-Alder reaction and the Overman rearrangement as key steps. The Overman r