199804-22-3

Basic information

• Product Name: N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE
• Synonyms: SULFO-HSAB;N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE;N-HYDROXYSULPHOSUCCINIMIDYL-4-AZIDOBENZOATE;Sulpho HSAB
• CAS NO: 199804-22-3
• Molecular Formula: C11H8N4O7S
• Molecular Weight: 340.27
• Product Categories: photoazide
• Mol File: 199804-22-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20-0°C
• CAS DataBase Reference: N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE(199804-22-3)
• EPA Substance Registry System: N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE(199804-22-3)

Safety Data

• Hazardous Substances Data: 199804-22-3(Hazardous Substances Data)

Usage

Description

N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is a versatile chemical compound utilized in bioconjugation and biotinylation processes. It is characterized by its water solubility and inability to cross cell membranes, which makes it suitable for the modification of primary amines in proteins, peptides, and other biomolecules. The hydroxysulfosuccinimide (sulfo-NHS) component of the compound facilitates the formation of stable amide bonds with primary amines, while the azide group allows for further click chemistry reactions, enhancing its utility in various biochemical and molecular biology applications.

Uses

Used in Biochemistry and Molecular Biology:
N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is used as a bioconjugation agent for the modification of primary amines in biomolecules. It enables the attachment of functional groups or other biomolecules to the target amines, facilitating various applications such as the study of protein-protein interactions, enzyme activity assays, and the development of biosensors.
Used in Biolabeling and Detection:
N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is used as a biolabeling reagent for the detection and visualization of biomolecules in biochemical and biological studies. The azide group in the compound allows for the attachment of fluorescent tags, affinity tags, or other reporter molecules through click chemistry, enhancing the sensitivity and specificity of detection methods.
Used in Drug Development:
In the pharmaceutical industry, N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is used as a tool for the development of targeted drug delivery systems. By conjugating drugs or drug carriers to specific biomolecules, it enables the selective delivery of therapeutic agents to diseased cells or tissues, improving the efficacy and reducing the side effects of treatments.
Used in Diagnostics:
N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is employed in the development of diagnostic assays and tests. N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE can be used to label antibodies, nucleic acids, or other diagnostic markers, allowing for the sensitive and specific detection of disease markers or pathogens in clinical samples.
Used in Research:
In academic and industrial research settings, N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE is used as a research tool for exploring the structure, function, and interactions of biomolecules. N-HYDROXYSULFOSUCCINIMIDYL-4-AZIDOBENZOATE enables the creation of novel bioconjugates and the investigation of biomolecular processes, contributing to the advancement of biological knowledge and the discovery of new therapeutic targets.