199865-05-9Relevant academic research and scientific papers
New multi-1,2,3-selenadiazole aromatic derivatives
Al-Smadi, Mousa,Ratrout, Samer
, p. 1126 - 1134 (2007/10/03)
The aromatic polyketones 3a-d are versatile compounds for the synthesis of the multi-1,2,3-selenadiazole aromatic derivatives 1a-d. The preparation starts with the reaction between the multi-bromomethylene benzene derivatives 2a-d and 4-hydroxy-acetophenone to give compounds 3a-d which are transformed through the reaction with semicarbazide hydrochloride or ethyl hydrazine carboxylate into the corresponding semicarbazones derivatives 4a-d or hydrazones 5a-d. The reaction with selenium dioxide leads to regiospecific ring closure of semicarbazones or hydrazones to give the multi-1,2,3-selenadiazole aromatic derivatives in high yield.
New many fold 1,2,3-selenadiazole aromatic derivatives
Al-Smadi, Mousa,Ratrout, Samer
, p. 887 - 891 (2007/10/03)
The many fold aromatic ketones 2a-d are versatile compounds for the synthesis of the many fold 1,2,3-selenadiazole aromatic derivatives 5a-d. The preparation starts with the reaction between the many fold bromomethylene benzene derivatives 1a-d and 4-hydroxyacetophenone, which are transformed through the reaction with semicarbazide hydrochloride or ethylhydrazine carboxylate into the corresponding semicarbazones derivatives 3a-d or hydrazones 4a-d. The reaction with selenium dioxide leads to regiospecific ring closure of semicarbazones or hydrazones to give the many fold 1,2,3-selenadiazole aromatic derivatives in high yield.
