19992-43-9 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
(1RS,3SR)-3-phenylcyclohexanamine is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its chiral nature allows for the creation of enantiomerically pure compounds, which is crucial for the development of effective and safe drugs and pesticides.
Used in Perfume and Fragrance Production:
(1RS,3SR)-3-phenylcyclohexanamine serves as a valuable building block in the production of perfumes and fragrances. Its unique structure contributes to the creation of distinct scents and aromas, enhancing the sensory experience of consumers.
Used in Organic Synthesis:
(1RS,3SR)-3-phenylcyclohexanamine is commonly employed as a versatile building block in organic synthesis. Its reactivity and structural features make it suitable for the construction of complex organic molecules, facilitating advancements in chemical research and development.
Used in Asymmetric Synthesis and Catalysis:
Due to its chiral properties, (1RS,3SR)-3-phenylcyclohexanamine is used in asymmetric synthesis and catalysis. It plays a pivotal role in the selective formation of enantiomers, which is essential for producing biologically active compounds with desired properties and minimizing unwanted side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 19992-43-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,9 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19992-43:
(7*1)+(6*9)+(5*9)+(4*9)+(3*2)+(2*4)+(1*3)=159
159 % 10 = 9
So 19992-43-9 is a valid CAS Registry Number.
19992-43-9Relevant academic research and scientific papers
Catalytic C(sp3)?H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ
Xu, Yan,Young, Michael C.,Wang, Chengpeng,Magness, David M.,Dong, Guangbin
supporting information, p. 9084 - 9087 (2016/07/26)
Herein, we report the palladium-catalyzed direct arylation of unactivated aliphatic C?H bonds in free primary amines. This method takes advantage of an exo-imine-type directing group (DG) that can be generated and removed in situ. A range of unprotected aliphatic amines are suitable substrates, undergoing site-selective arylation at the γ-position. Methyl as well as cyclic and acyclic methylene groups can be activated. Furthermore, when aniline-derived substrates were used, preliminary success with δ-C?H arylation was achieved. The feasibility of using the DG component in a catalytic fashion was also demonstrated.
Stereoselective synthesis of carbocyclic analogues of the nucleoside Q precursor (PreQ0)
Llona-Minguez, Sabin,Mackay, Simon P.
supporting information, p. 1333 - 1338 (2014/07/22)
A convergent and stereoselective synthesis of chiral cyclopentyl- and cyclohexylamine derivatives of nucleoside Q precursor (PreQ0) has been accomplished. This synthetic route allows for an efficient preparation of 4-substituted analogues with
