19997-23-0

Basic information

• Product Name: spiro[(6,6-dimethyl-3-(4-nitrophenyl)-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)]
• Synonyms: spiro[(6,6-dimethyl-3-(4-nitrophenyl)-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)]
• CAS NO: 19997-23-0
• Molecular Weight: 411.455
• Mol File: 19997-23-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: spiro[(6,6-dimethyl-3-(4-nitrophenyl)-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](CAS DataBase Reference)
• NIST Chemistry Reference: spiro[(6,6-dimethyl-3-(4-nitrophenyl)-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](19997-23-0)
• EPA Substance Registry System: spiro[(6,6-dimethyl-3-(4-nitrophenyl)-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](19997-23-0)

Safety Data

• Hazardous Substances Data: 19997-23-0(Hazardous Substances Data)

Upstream product

• 7560-71-6 2,2'-(4-nitrophenylmethylene)bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) 
• 35024-12-5 (4,4-dimethyl-2,6-dioxo-cyclohexyl)-phenyl-iodonium betaine 
• 555-16-8 4-nitrobenzaldehdye 
• 126-81-8 dimedone 

Relevant articles and documents

Selective synthesis of spiro and dispiro compounds using Mn(III)-based oxidation of tetracarbonyl compounds

The Mn(III)-based oxidation of methylenebis(cyclohexanedione)s and methylenebis(piperidinedione)s as a tetracarbonyl compound was investigated under various conditions, selectively producing spiro dihydrofurans and dispiro cyclopropanes depending on the solvent. The mechanism for the formation of the spiro dihydrofurans and dispiro cyclopropanes was discussed. In addition, a simple synthesis of a new type of alkaloid, 3,4,6,7,8,10-hexahydro-1H-pyrano[3,2-c:5,6-c’]dipyridine-1,9(2H)-diones, was demonstrated.

A new iodonium ylide-based three-component reaction leading to 2-spirosubstituted dihydrofurans under microwave irradiation

A new iodonium ylide-based three-component reaction for the synthesis of highly functionalized 2-spirosubstituted dihydrofurans starting from readily available common reactants has been developed under microwave irradiation. The procedure is facile, avoid

Selective formation of spiro dihydrofurans from one-pot reaction of dimedone with BrCN and aldehydes in the presence of Et3N

Reaction of 5,5-dimethylcyclohexane-1,3-dione (dimedone), aldehydes and cyanogen bromide in the presence of triethylamine leads to the selective formation of spiro dihydrofurans in moderate to good yields at room temperature.