20000-51-5Relevant academic research and scientific papers
BENZO-HETEROCYCLIC COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING CANCER DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT
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Paragraph 0108-0110; 0113-0114, (2021/12/30)
A novel benzoheterocycle compound or a pharmaceutically acceptable salt thereof showed a high anti-proliferative effect against cancer cell lines. Using this, a pharmaceutical composition for preventing or treating cancer disease can comprise the compound
A fluorinated phenylbenzothiazole arrests the trypanosoma cruzi cell cycle and diminishes the infection of mammalian host cells
Crispim, Marcell,Da Silva, Marcelo Santos,Elias, Maria Carolina,Girard, RichardM. B. M.,Silber, Ariel Mariano,Cuevas-Hernández, Roberto I.,Martínez-Cerón, Sarai,Trujillo-Ferrara, José G.
, (2020/02/04)
Chagas disease (CD) is a human infection caused by Trypanosoma cruzi. CD was traditionally endemic to the Americas; however, due to migration it has spread to countries where it is not endemic. The current chemotherapy to treat CD induces several side eff
Visible-light-promoted synthesis of benzothiazoles from 2-aminothiophenols and aldehydes
Ye, Lin-miao,Chen, Jie,Mao, Peng,Mao, Zhi-feng,Zhang, Xue-jing,Yan, Ming
supporting information, p. 874 - 876 (2017/02/18)
A visible-light-promoted synthesis of benzothiazoles from 2-aminothiophenols and aldehydes has been developed. A wide range of aromatic, heteroaromatic and aliphatic aldehydes were successfully applied. The benzothiazole products were prepared in good yields. The reaction was carried out in the absence of transition-metal catalysts and extra additives. A radical reaction pathway was proposed.
Liquid-phase synthesis of 2-substituted benzimidazoles, benzoxazoles and benzothiazoles
Chen, Chinpiao,Chen, Yi-Jing
, p. 113 - 115 (2007/10/03)
A novel acid fluoride for use in the liquid-phase synthesis of substituted benzimidazoles, benzoxazoles and benzothiazoles was developed. Its synthetic utility is exemplified by a structurally diverse set of aromatic heterocycles. Final cleavage is achiev
