200007-25-6Relevant articles and documents
Non-ATP-competiveness FGFR1 (fibroblast growth factor receptor 1) inhibitor and application thereof
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Paragraph 0023-0024; 0027, (2017/08/31)
The invention belongs to the field of pharmacy and particularly relates to application of a specific non-ATP-competiveness FGFR1 (fibroblast growth factor receptor 1) inhibitor in preparing anticancer medicine and medicine for treating cancer-related diseases. The invention further relates to a small molecule compound L16H50 which can inhibit FGFR1 and activation of a signal channel of the FGFR1 in a non-ATP-dependent mode. Therefore, multiplication and survival of cancer cells are inhibited, and good in-vitro and in-vivo anticancer effects are further given to play.