20004-92-6

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 20004-93-7 2-(4-chlorophenyl)-5-phenylvaleric acid 
• 14087-98-0 6-(4-Chloro-phenyl)-6,7,8,9-tetrahydro-benzocyclohepten-5-one 
• 118386-78-0 6-(4-Chloro-phenyl)-6,7,8,9-tetrahydro-benzocyclohepten-5-one oxime 
• 113843-01-9 3-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-1-benzazocin-2-one 

Relevant academic research and scientific papers

Antihypertensive thiocarbamoylascetonitrile compounds

Disclosed are antihypertensive pharmaceutical compositions and compounds which include the thiocarbamoylacetonitrile having the formula: STR1 wherein: R1 is selected from the group consisting of hydrogen, a C1 to C6 alkyl, a C3 to C6 cycloalkyl or --(CH2)n --A (where A is selected from the group consisting of a C6 to C12 aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group constituted by 9 or 10 atoms, each of which may be substituted by at least one substitute group selected from a C1 to C6 alkyl and a halogen and n is 0 or an integer of 1 to 6), R2 represents a C1 to C10 alkyl, and Ar represents an aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group, each of which may be substituted by at least one substituent group selected from the group consisting of a C1 to C6 alkyl, a C1 to C6 alkoxy, a C2 to C7 alkylcarbonyl, a C7 to C6 dialkylamino, amino, formylamino, a C2 to C7 alkylcarbonylamino, a halogen, cyano, nitro, hydroxyl, a C1 to C6 alkylthio, a C6 to C12 arylsulfinyl, a C1 to C6 alkylsulfinyl, a C6 to C12 alkylsulfonyl, a C6 to C12 arylsulfonyl, aminosulfonyl, a C1 to C6 alkylaminosulfonyl, a C2 to C6 dialkylaminosulfonyl, trifluoromethyl and imidazolyl.