200064-98-8

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-bromophenyl)butan-2-one is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into various drug molecules, contributing to the development of new medications.
Used in Organic Compounds Synthesis:
1-(4-bromophenyl)butan-2-one is used as a building block in the synthesis of other organic compounds, facilitating the creation of a wide range of chemical products.
Used in Fragrance Industry:
1-(4-bromophenyl)butan-2-one is used as a component in the production of fragrances for its strong, sweet, and fruity odor, enhancing the scent profiles of various perfumes and scented products.
Used in Flavoring Agents Industry:
1-(4-bromophenyl)butan-2-one is used in the production of flavoring agents, leveraging its distinctive fruity aroma to improve the taste and smell of food products and beverages.
It is important to handle this chemical with care, as it can be irritant to the skin, eyes, and respiratory system and should be used in a well-ventilated area with proper personal protective equipment.

Upstream product

• 999-75-7 ethylzinc iodide 
• 29816-58-8 1-Bromo-4-((E)-2-nitro-but-1-enyl)-benzene 
• 149652-50-6 2-(4-bromophenyl)-N-methoxy-N-methylacetamide 
• 925-90-6 ethylmagnesium bromide 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 

Downstream Products

• 1146-98-1 bromindione 

Relevant academic research and scientific papers

ANTIMICROBIAL COMPOUNDS AND METHODS

The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.

Synthesis and serotonin transporter activity of sulphur-substituted α-alkyl phenethylamines as a new class of anticancer agents

The discovery that some serotonin reuptake transporter (SERT) ligands have the potential to act as pro-apoptotic agents in the treatment of cancer adds greatly to their diverse pharmacological application. 4-Methylthioamphetamine (MTA) is a selective ligand for SERT over other monoamine transporters. In this study, a novel library of structurally diverse 4-MTA analogues were synthesised with or without N-alkyl and/or C-α methyl or ethyl groups so that their potential SERT-dependent antiproliferative activity could be assessed. Many of the compounds displayed SERT-binding activity as well as cytotoxic activity. While there was no direct correlation between these two effects, a number of derivatives displayed anti-tumour effects in lymphoma, leukaemia and breast cancer cell lines, showing further potential to be developed as possible chemotherapeutic agents.

New Odorless Protocols for the Synthesis of Aldehydes and Ketones from Thiol Esters

Dodecanethiol esters derived from odorless dodecanethiol proved to be suitable substrates for Pd-catalyzed reduction with triethylsilane, coupling with organozinc reagents, and coupling with terminal acetylenes.

A novel ketone synthesis by a palladium-catalyzed reaction of thiol esters and organozinc reagents

A variety of ketones have been prepared by a palladium-catalyzed reaction of ethanethiol esters with organozinc reagents. Various functional groups, including esters, ketones, aromatic halides and aldehydes, tolerate the reaction conditions. The reaction can also be applied to the synthesis of α-amino ketones using the corresponding L-α-amino thiol esters without racemization.