200182-37-2

Upstream product

• 288395-86-8 Acetic acid (3aS,3bR,10bR,11S,12S,12aS)-6-acetoxy-11-hydroxy-4-(4-methoxy-benzyl)-2,2-dimethyl-5-oxo-3a,3b,4,5,10b,11,12,12a-octahydro-1,3,7,9-tetraoxa-4-aza-dicyclopenta[a,h]phenanthren-12-yl ester 
• 6493-77-2 methyl cyclohex-3-ene-1-carboxylate 
• 200182-36-1 Acetic acid (3aS,3bR,10bR,11S,12R,12aS)-6-acetoxy-11-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyl)-2,2-dimethyl-5-oxo-3a,3b,4,5,10b,11,12,12a-octahydro-1,3,7,9-tetraoxa-4-aza-dicyclopenta[a,h]phenanthren-12-yl ester 
• 200182-35-0 Acetic acid (1S,2R,4aS,11bR)-7-acetoxy-1-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyl)-6-oxo-1,2,4a,5,6,11b-hexahydro-[1,3]dioxolo[4,5-j]phenanthridin-2-yl ester 
• 288395-85-7 4-(1-Ethoxy-ethoxy)-benzo[1,3]dioxole-5-carboxylic acid [(1R,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl]-(4-methoxy-benzyl)-amide 
• 200182-34-9 C₂₈H₃₅NO₇Si 
• 200182-38-3 1-(tert-butyl-dimethyl-silanyloxy)-2,7-dihydroxy-5-(4-methoxy-benzyl)-1,4a,5,11b-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one 
• 200182-33-8 4-Hydroxy-benzo[1,3]dioxole-5-carboxylic acid [(1R,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl]-(4-methoxy-benzyl)-amide 
• 200182-32-7 4-(1-Ethoxy-ethoxy)-benzo[1,3]dioxole-5-carboxylic acid [(1R,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl]-amide 
• 288395-75-5 (+)-5-(tert-butyl-dimethylsilanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid methyl ester 
• 200182-31-6 (+)-5-(tert-butyldimethylsilanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid 
• 1028277-29-3 tert-Butyl-((1R,2S,6R)-4-isocyanato-7-oxa-bicyclo[4.1.0]hept-3-en-2-yloxy)-dimethyl-silane 
• 288395-83-5 5-butyryloxy-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid methyl ester 
• 192210-65-4 5-bromo-4-(1-ethoxyethoxy)-2H-benzo[d]1,3-dioxolane 

Downstream Products

• 29477-83-6 narciclasine 
• 288395-87-9 6,12-dihydroxy-4-(4-methoxy-benzyl)-2,2-dimethyl-3b,4,12,12a-tetrahydro-3aH-1,3,7,9-tetraoxa-4-aza-dicyclopenta[a,h]phenanthren-5-one 

Relevant academic research and scientific papers

Studies on the narciclasine alkaloids: Total synthesis of (+)- narciclasine and (+)-pancratistatin

Enantioselective total syntheses of the antimmor alkaloids, (+)- narciclasine and (+)-pancratistatin, are reported. These syntheses feature a stereo- and regiocontrolled aryl enamide photocyclization to construct a common, advanced intermediate possessing a transfused BC substructure. Differential functional group interchange in the C-ring of this phenanthridone core structure allows for the production of the two target natural products in enantiomerically pure form.