200184-45-8 Usage
Chemical class
N-acylpyrrolidines
Explanation
1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- belongs to a class of organic compounds known as N-acylpyrrolidines, which are derivatives of pyrrolidine, a cyclic amine.
Explanation
The parent compound of this specific compound is pyrrolidine, a cyclic amine.
Explanation
1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- is the tert-butyl ester of the (2S)-enantiomer of 2-formylazetidine-1-carboxylic acid.
Explanation
The stereochemistry of 1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- is important in determining its biological activity and potential applications. It is the (2S)-enantiomer of 2-formylazetidine-1-carboxylic acid.
Explanation
1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- is commonly used in the pharmaceutical industry as a building block for the synthesis of various compounds, including potential drug candidates.
Explanation
Due to its unique properties and stereochemistry, 1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- has potential value in medicinal chemistry and drug development.
Explanation
The compound contains an azetidinecarboxylic acid, an aldehyde, and an ester functional group, which contribute to its reactivity and potential applications in synthesis.
Explanation
The compound has a chiral center at the 2-position, which is responsible for the (2S)-enantiomer designation.
Explanation
1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- is likely to be soluble in organic solvents, such as ethanol, methanol, or acetonitrile, due to its ester functional group.
Explanation
As an organic compound, 1-Azetidinecarboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)- is expected to be stable under normal conditions, such as room temperature and pressure, in the absence of strong acids or bases.
Parent compound
Pyrrolidine
Ester type
tert-butyl ester
Stereochemistry
(2S)-enantiomer
Pharmaceutical industry use
Building block for synthesis
Potential value
Medicinal chemistry and drug development
Functional groups
Azetidinecarboxylic acid, aldehyde, ester
Chirality
Chiral center at the 2-position
Solubility
Soluble in organic solvents
Stability
Stable under normal conditions
Check Digit Verification of cas no
The CAS Registry Mumber 200184-45-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,0,1,8 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 200184-45:
(8*2)+(7*0)+(6*0)+(5*1)+(4*8)+(3*4)+(2*4)+(1*5)=78
78 % 10 = 8
So 200184-45-8 is a valid CAS Registry Number.
200184-45-8Relevant academic research and scientific papers
Enantioselective hydroformylation of N-vinyl carboxamides, allyl carbamates, and allyl ethers using chiral diazaphospholane ligands
McDonald, Richard I.,Wong, Gene W.,Neupane, Ram P.,Stahl, Shannon S.,Landis, Clark R.
supporting information; experimental part, p. 14027 - 14029 (2011/01/04)
Rhodium complexes of diazaphospholane ligands catalyze the asymmetric hydroformylation of N-vinyl carboxamides, allyl ethers, and allyl carbamates; products include 1,2- and 1,3-aminoaldehydes and 1,3-alkoxyaldehydes. Using glass pressure bottles, short reaction times (generally less than 6 h), and low catalyst loading (commonly 0.5 mol %), 20 substrates are successfully converted to chiral aldehydes with useful regioselectivity and high enantioselectivity (up to 99% ee). Chiral Roche aldehyde is obtained with 97% ee from the hydroformylation of allyl silyl ethers. Commonly difficult substrates such as 1,1- and 1,2-disubstituted alkenes undergo effective hydroformylation with 89-97% ee and complete conversion for six examples. Palladium-catalyzed aerobic oxidative amination of allyl benzyl ether followed by enantioselective hydroformylation yields the β3-aminoaldehyde with 74% ee.
