200278-95-1Relevant articles and documents
Copper-Catalyzed sp3 C-H Aminative Cyclization of 2-Alkyl-N-arylbenzamides: An Approach for the Synthesis of N-Aryl-isoindolinones
Nozawa-Kumada, Kanako,Kadokawa, Jun,Kameyama, Takehiro,Kondo, Yoshinori
supporting information, p. 4479 - 4481 (2015/09/28)
The synthesis of isoindolinones via copper-catalyzed sp3 C-H functionalization of 2-alkyl-N-substituted benzamides is described. This process does not require the preparation of halogenated substitutes, expensive transition metals, or toxic Sn or CO gas. This method provides an efficient approach to generate various functionalized isoindolinones.
Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists
Sum, Fuk-Wah,Dusza, John,Delos Santos, Efren,Grosu, George,Reich, Marvin,Du, Xumei,Albright, J. Donald,Chan, Peter,Coupet, Joseph,Ru, Xun,Mazandarani, Hossein,Saunders, Trina
, p. 2195 - 2198 (2007/10/03)
Novel tricyclic benzazepine derivatives were synthesized as arginine vasopressin (AVP) antagonists. Several tricyclic compounds showed potent antagonistic activity in rat AVP receptors V1a and V2. Derivatives containing pyrrolo-tricy