200338-34-7Relevant academic research and scientific papers
Total synthesis of luzopeptin E2
Ciufolini, Marco A.,Valognes, Delphine,Xi, Ning
, p. 2493 - 2495 (2007/10/03)
The self-assembly of the 32-membered macrocycle of iuzopeptin E2 (1) has been accomplished by cyclodimerization of a terminally unprotected pentapeptide monomer. This is the key step of the first total synthesis of this macrocyclic antitumor decadepsipept
Elevated conformational rigidity in dipeptides incorporating piperazic acid derivatives
Xi, Ning,Alemany, Lawrence B.,Ciufolini, Marco A.
, p. 80 - 86 (2007/10/03)
N-Acyl derivatives of piperazic acids display an unusual degree of conformational rigidity. As a consequence, α-N-coupling of a piperazic acid of given configuration (D or L) with an α-aminoacyl unit of opposite configuration (L or D) produces a 'heteroch
