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1-(Chloromethyl)-4-cyclopropylbenzene is a chemical compound characterized by a molecular formula of C10H11Cl. It features a chloromethyl-substituted cyclopropylbenzene with a 1-chloromethyl and a 4-cyclopropyl substituent on the benzene ring. 1-(chloromethyl)-4-cyclopropylbenzene is recognized for its potential as a structural analog to other biologically active compounds, making it a valuable asset in the fields of medicinal chemistry and drug development.

20034-53-1

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20034-53-1 Usage

Uses

Used in Pharmaceutical Synthesis:
1-(Chloromethyl)-4-cyclopropylbenzene is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of biologically active compounds, contributing to the development of new medications.
Used in Agrochemical Production:
1-(chloromethyl)-4-cyclopropylbenzene also serves as an intermediate in the production of agrochemicals, which are chemicals specifically designed to benefit crop or livestock production. Its role in this industry highlights its versatility and potential applications in different sectors.
Used in Organic Compound Preparation:
1-(Chloromethyl)-4-cyclopropylbenzene is employed as a building block for the preparation of various substituted benzene derivatives. Its structural properties make it a suitable candidate for the synthesis of a diverse array of organic compounds, further expanding its utility in chemical research and development.
Used in Medicinal Chemistry and Drug Development:
Due to its potential as a structural analog to other biologically active compounds, 1-(chloromethyl)-4-cyclopropylbenzene holds promise in medicinal chemistry and drug development. Its unique structure can be leveraged to design and develop new drugs with improved efficacy and selectivity, ultimately benefiting the healthcare industry.

Check Digit Verification of cas no

The CAS Registry Mumber 20034-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,0,3 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 20034-53:
(7*2)+(6*0)+(5*0)+(4*3)+(3*4)+(2*5)+(1*3)=51
51 % 10 = 1
So 20034-53-1 is a valid CAS Registry Number.

20034-53-1Downstream Products

20034-53-1Relevant academic research and scientific papers

THIAZALOPYRROLIDINE INHIBITORS OF ROR-GAMMA

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Paragraph 00203, (2014/11/13)

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Iron-catalyzed cyclopropanation in 6 M KOH with in situ generation of diazomethane

Morandi, Bill,Carreira, Erick M.

scheme or table, p. 1471 - 1474 (2012/07/13)

Diazomethane is a common and versatile reagent in organic synthesis whose broader use is generally impeded by its explosiveness and toxicity. Here we report that a simple iron porphyrin complex catalyzes the cyclopropanation of styrenes, enynes, and dienes under the demanding conditions [aqueous 6 molar potassium hydroxide (KOH) solution, open to air] necessary for the in situ generation of diazomethane from a water-soluble diazald derivative. A biphasic reaction medium arising from the immiscibility of the olefin substrates with water appears essential to the overall efficiency of the process. The work we describe highlights an approach to catalysis with untoward reactive intermediates, in which the conditions for their generation under operationally safe regimes dictate catalyst selection.

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