200342-94-5Relevant academic research and scientific papers
Diastereoselective epoxidation of dipeptide olefins
Romeo, Sergio,Rich, Daniel H.
, p. 7187 - 7190 (2007/10/02)
m-Chloroperbenzoic acid (MCPBA) epoxidation of dipeptide olefins proceeds in high syndiastereoselectivity (38:1-300:1). This is partially caused by conformational constants introduce by the side chain that orients the allylic NH in a favorable position for hydrogen bonding to MCPBA. The possibility of an additional hydrogen bond between the N-terminal NH and MCPBA is excluded.
