200346-83-4

Basic information

• Product Name: 4-(Phosphonooxy)butyric acid 2(S)-[4-[4-[4-[4-[5(R)-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3(R)-ylmethoxy]phenyl]piperazin-1-yl]phenyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-1(S)-methylbutyl ester
• Synonyms: SCH-59884; 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(1S,2S)-1-ethyl-2-{[4-(phosphonooxy)butanoyl]oxy}propyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
• CAS NO: 200346-83-4
• Molecular Formula: C₄₁H₄₉F₂N₈O₉P
• Molecular Weight: 866.8465
• Mol File: 200346-83-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 968.985°C at 760 mmHg
• Flash Point: 539.823°C
• Density: 1.443g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 4-(Phosphonooxy)butyric acid 2(S)-[4-[4-[4-[4-[5(R)-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3(R)-ylmethoxy]phenyl]piperazin-1-yl]phenyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-1(S)-methylbutyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Phosphonooxy)butyric acid 2(S)-[4-[4-[4-[4-[5(R)-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3(R)-ylmethoxy]phenyl]piperazin-1-yl]phenyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-1(S)-methylbutyl ester(200346-83-4)
• EPA Substance Registry System: 4-(Phosphonooxy)butyric acid 2(S)-[4-[4-[4-[4-[5(R)-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3(R)-ylmethoxy]phenyl]piperazin-1-yl]phenyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-1(S)-methylbutyl ester(200346-83-4)

Safety Data

• Hazardous Substances Data: 200346-83-4(Hazardous Substances Data)

Upstream product

• 171228-49-2 posaconazote 
• 221615-78-7 C₅₅H₆₁F₂N₈O₉P 

Downstream Products

• 221615-76-5 4-Hydroxy-butyric acid (1S,2S)-2-{4-[4-(4-{4-[(3R,5R)-5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-3-ylmethoxy]-phenyl}-piperazin-1-yl)-phenyl]-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl}-1-methyl-butyl ester 

Relevant articles and documents

TETRAHYDROFURAN PHOSPHATE- AND HYDROXY ESTERS, AS PRODRUGS FOR THE CORRESPONDING ANTIFUNGAL AGENT

A compound of formula (I) wherein G is H or PO3H2 or a pharmaceutical acceptable salt thereof, pharmaceutical compositions containing such compounds and method of using such compounds or pharmaceutical compositions containing them to treat or prevent fungal infection are disclosed.