200347-56-4Relevant academic research and scientific papers
The reactions of nitrones with indoles
Chalaye-Mauger, Hélène,Denis, Jean-No?l,Averbuch-Pouchot, Marie-Thérèse,Vallée, Yannick
, p. 791 - 804 (2007/10/03)
The reaction of nitrones with various indole derivatives has been studied. When the reaction was promoted by C1SiMe3, the isolated products were 3,3'-diindolylalkanes. With HC1 as the activating reagent, 3- indolylhydroxylamines were isolated. The diastereoselectivity of this condensation with a nitrone derived from cysteine was investigated. A method for the introduction of an alkylhydroxylamino group onto position 2 of indole, the synthesis of three natural 3,3'-diindolylalkanes and of non- symmetric diindolylalkanes are also reported. (C) 2000 Elsevier Science Ltd.
The reaction of nitrones with indoles. Synthesis of asymmetrical diindolylalcanes
Denis, Jean-Noel,Mauger, Helene,Vallee, Yannick
, p. 8515 - 8518 (2007/10/03)
The reaction of nitrones with indoles in the presence of HCl gives indolyl N-hydroxylamines. In the presence of Me3SiCl symmetrical diindolylalcanes are obtained. A synthesis of asymmetrical diindolylalcanes and the syntheses of three natural symmetrical diindolylalcanes are reported.
