200511-04-2Relevant academic research and scientific papers
Synthesis of chiral ferrocenyl-substituted β-amino cyclopentadienes and their complexation to transition metals
Schwink, Lothar,Knochel, Paul,Eberle, Thomas,Okuda, Jun
, p. 7 - 9 (1998)
CBS reduction of the (chloroacyl)ferrocenes 3 provides the chloro alcohols 5 with ≥98% ee, which upon treatment with cyclopentadienides yield the chiral β- or γ-hydroxy cyclopentadienes 6 and 7. The hydroxyl function of 6 and 7 can be substituted with full retention of configuration by a range of N- or S-nucleophiles, giving efficient access to the optically active linked amino-cyclopentadienyl ligands 11-13. These were complexed to an iron center, yielding a ferrocenyl diamine with a large bite angle between the nitrogen donor atoms. Furthermore the first chelating complexation reaction to titanium is presented.
