20052-60-2

Usage

Uses

Used in Pharmaceutical Applications:
7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE is used as a therapeutic agent for various health conditions due to its antioxidant and anti-inflammatory properties. It is particularly effective in managing diabetes, cardiovascular diseases, and cancer, as it has been studied for its potential to alleviate these conditions.
Used in Traditional Medicine:
In traditional medicine, 7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE is used for its anti-microbial and anti-fungal properties, making it a valuable component in treating infections and promoting overall health.
Used in Food Industry:
7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE is used as a natural preservative and flavor enhancer in the food industry, thanks to its presence in fruits and vegetables like cherries and celery. Its antioxidant properties also contribute to the overall health benefits of these food products.
Used in Cosmetics Industry:
In the cosmetics industry, 7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE is used for its anti-inflammatory and antioxidant properties, making it a valuable ingredient in skincare products. It helps to reduce inflammation, promote skin health, and protect against environmental damage.
Used in Research:
7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE is used as a subject of interest in research studies, as it has shown promise in various fields, including medicine, pharmacology, and nutrition. Its potential applications and therapeutic effects are being further investigated to explore its full potential in various industries.

InChI:InChI=1/C12H14O3/c1-7-4-8(13)5-10-11(7)9(14)6-12(2,3)15-10/h4-5,13H,6H2,1-3H3

Upstream product

• 504-15-4 orcinol 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 541-47-9 3-Methylbutenoic acid 
• 37637-88-0 N-formamido-3-methyl-2-butenamide 
• 6153-39-5 5-Methylresorcinol monohydrate 

Downstream Products

• 128890-32-4 N-Phenyl-2-(2,2,5-trimethyl-4-oxo-chroman-7-yloxy)-acetamide 
• 128890-37-9 Toluene-4-sulfonic acid 2,2,5-trimethyl-4-oxo-chroman-7-yl ester 
• 133035-36-6 N-p-Tolyl-2-(2,2,5-trimethyl-4-oxo-chroman-7-yloxy)-acetamide 
• 128890-35-7 N-(4-Chloro-phenyl)-2-(2,2,5-trimethyl-4-oxo-chroman-7-yloxy)-acetamide 
• 133035-35-5 N-o-Tolyl-2-(2,2,5-trimethyl-4-oxo-chroman-7-yloxy)-acetamide 
• 128890-33-5 N-(2-Chloro-phenyl)-2-(2,2,5-trimethyl-4-oxo-chroman-7-yloxy)-acetamide 
• 128890-38-0 4-Bromo-benzenesulfonic acid 2,2,5-trimethyl-4-oxo-chroman-7-yl ester 
• 128890-40-4 2,2,5-Trimethyl-7-(4-nitro-benzyloxy)-chroman-4-one 
• 121404-46-4 7-Cyclohexyloxy-2,2,5-trimethyl-chroman-4-one 
• 121404-48-6 7-Benzyloxy-2,2,5-trimethyl-chroman-4-one 
• 121404-50-0 7-(4-Chloro-benzyloxy)-2,2,5-trimethyl-chroman-4-one 
• 121404-49-7 7-(2-Chloro-benzyloxy)-2,2,5-trimethyl-chroman-4-one 
• 70442-00-1 7-Methoxy-2,2,5-trimethyl-2H-chromene 
• 94244-09-4 2,2,5-Trimethyl-7-prop-2-ynyloxy-2H-chromene 

Relevant academic research and scientific papers

Preparation of 2,2-dimethylchroman-4-ones from 5-alkyl-substituted resorcinols: Microwave-assisted synthesis and theoretical calculations

The influence of different 5-alkyl-substituted resorcinols on the formation of 2,2-dimethylchroman- 4-ones is examined experimentally and theoretically. Structures are fully assigned by means of experimental and theoretical 13C and 1H NMR chemical shifts.

FUSED BICYCLIC COMPOUND

The present invention provides a novel fused bicyclic compound having an affinity to a receptor of mineral corticoid (MR), shown by the formula [I]: wherein the ring A is a benzene ring having a substituent R1, fused to an adjacent 6-membered h

Synthesis of 1-aryl-3-methyl-but-2-en-1-ones intermediates for the synthesis of chromanone derivatives

A convenient preparation of hitherto unknown compounds 3a, 4a, 3c, 4b and 4c by Friedel-Crafts reaction of active phenol derivatives and 3,3-dimethylacrylol chloride using anhydrous aluminium iodide as the condensing agent is described.

SYNTHESIS OF ANALOGUES OF NATURAL PRECOCENES CONTAINING A 5-METHYL SUBSTITUENT

The synthesis of benzopyran compounds (VII a-q), analogues of precocene I (I) substituted on C-5 in the aromatic ring with a methyl group, is described.

α, β-Unsaturated N-Acylureas as Useful Intermediates for the Synthesis of Indanones, Chromanones and Coumarins

α,β-Unsaturated N-acylureas, viz-N-formamido-2-butenamide (I), N-formamido-3-methyl-2-butenamide (II) and N-formamido-3-phenyl-2-propenamide (III) react with aryl alkyl ethers in the presence of PPA to afford the corresponding crotonophenones and chalcones (IV) at lower temperature and 1-indanones (V) at a higher temperature.Reactions of I and II with phenols in the presence of PPA afford the 4-chromanones (VI), while III gives 3,4-dihydro-4-phenylcoumarins (VII) in excellent yields.