200571-82-0Relevant academic research and scientific papers
3,4-Dihydroquinazoline derivatives as novel selective T-type Ca 2+ channel blockers
Lee, Yong Sup,Lee, Bum Hoon,Park, Seong Jun,Kang, Soon Bang,Rhim, Hyewhon,Park, Jin-Yong,Lee, Jung-Ha,Jeong, Seong-Woo,Lee, Jae Yeol
, p. 3379 - 3384 (2004)
For LVA T-type Ca2+ channel blockers, 3,4-dihydroquinazoline derivatives as new scaffolds were prepared and evaluated for the inhibitory activity against two members of the recombinant T-type Ca2+ channel family. Among them, 8a (KYS0
3,4-Dihydroquinazoline derivatives as T-type calcium channel blockers and method of preparing the same
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Page/Page column 10-11, (2008/06/13)
The present invention relates to 3,4-dihydroquinazoline derivatives as T-type calcium channel blockers and a method of preparing the same. The present invention further relates to a composition comprising the same. The composition comprising the 3,4-dihyd
3,4-Dihydroquinazoline derivatives as T-type calcium channel blockers and method of preparing the same
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Page/Page column 8, (2008/06/13)
The present invention relates to 3,4-dihydroquinazoline derivatives as T-type calcium channel blockers and a method of preparing the same. The present invention further relates to a composition comprising the same. The composition comprising the 3,4-dihyd
Solid-phase synthesis of 3,4-dihydroquinazoline
Wang, Fengjiang,Hauske, James R.
, p. 8651 - 8654 (2007/10/03)
A novel, facile and efficient method for the synthesis of aryl iminophosphorane has been developed by treating a series of Ar-NH2 (1) attached to a solid support with Ph3P and diethyl azodicarboxylate at room temperature. The resulting solid-supported cinnamyl iminophosphorane (4) was treated with an aryl isocyanate to generate the corresponding solid-supported carbodiimide (5), which upon exposure to a secondary amine underwent 1,2-addition followed by an intramolecular Michael addition to afford the desired 3,4-dihydroquinazoline (7).
