200711-17-7Relevant academic research and scientific papers
A simple method for the synthesis of unsymmetrical ureas
Kitteringham,Shipton,Voyle
, p. 1937 - 1943 (2000)
A simple one pot procedure for the synthesis of N,N'-unsymmetrical ureas using phenyl chloroformate in THF is described.
1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT(2C) receptor inverse agonists
Bromidge, Steven M.,Davies, Susannah,Duckworth,Forbes, Ian T.,Jones, Graham E.,Jones, Jerome,King, Frank D.,Blackburn, Thomas P.,Holland, Vicky,Kennett, Guy A.,Lightowler, Sean,Middlemiss, Derek N.,Riley, Graham J.,Trail, Brenda,Wood, Martyn D.
, p. 1867 - 1870 (2007/10/03)
Bisarylmethoxyethers have been identified with nanomolar 5-HT(2C) affinity and selectivity over both 5-HT(2A) 5-HT(2A) and 5-HT(2B) receptors. Compounds such as 1, 2, 8, 12, 14 and 18 have potent oral activity in a centrally mediated pharmacodynamic model
