200728-85-4

Upstream product

• 141410-31-3 1,2,7-Trideoxy-7-iodo-3,4:5,6-di-O-isopropylidene-L-manno-hept-1-enitol 
• 141410-30-2 1,2-Dideoxy-3,4:5,6-di-O-isopropylidene-L-manno-hept-1-enitol 
• 113831-73-5 6,7-Didesoxy-2,3;4,5-di-O-isopropyliden-L-manno-hept-6-enose-trimethylendithioacetal 
• 200868-50-4 (1S,2S,3S)-1,2-dibenzyloxy-3-tert-butyldimethylsilylcyclohex-4-ene 
• 1026431-53-7 ((1R,2S,3S,4S,6R)-3,4-Bis-benzyloxy-bicyclo[4.1.0]hept-2-yl)-tert-butyl-dimethyl-silane 
• 200707-77-3 C₂₁H₂₃IO₂ 
• 200707-84-2 (1S,2S,3R,4S,6R)-3,4-Bis-benzyloxy-6-methyl-cyclohexane-1,2-diol 
• 141436-49-9 1D-(1,2,5/3,4)-1,2:3,4-Di-O-isopropylidene-5-C-methyl-1,2,3,4-cyclohexanetetrol 

Downstream Products

• 110892-05-2 1D-(1,2,5/3,4)-1,2,3,4-tetra-O-benzoyl-5-C-methyl-1,2,3,4-cyclohexanetetrol 

Relevant academic research and scientific papers

Synthesis of pseudo-sugars based on desymmetrization of dienylsilanes

A synthesis of pseudo-sugars using the desymmetrization of a dienylsilane, followed by a stereocontrolled introduction of the hydroxymethyl group at C5, is described. The CH2OH group at C5 was elaborated using either a regioselective cyclopropane-ring opening or a [2,3]-Wittig rearrangement.

Radical cyclisation of hept-1-enitols

7-Deoxy-7-iodohept-1-enitols react intramolecularly to give 5-carba analogues of pyranoses (pseudo sugars) by the action of tributyltin hydride, which generates a radical at C-7.The configuration at the new chiral centre depends on the relative orientatio