200798-59-0Relevant academic research and scientific papers
Cycloadditions of highly functionalized C6-synthons to cyclic nitrones
Closa, Montserrat,De March, Pedro,Figueredo, Marta,Font, Josep,Soria, Angeles
, p. 16803 - 16816 (1997)
The 1,3-dipolar cycloaddition of cyclic nitrones to several C6 α,β- unsaturated esters and lactones with different functionalities has been studied. All these olefins have shown high stereoselectivity, with a predominance of the exo or endo transition state for the cis or trans dipolarophiles, respectively. The antifacial approach is favoured in the reactions with γ-substituted hexenolides and also with the substituted nitrone 21.
