20081-63-4

Upstream product

• 120341-51-7 1,4-Bis-(2,4,6-trimethoxy-phenyl)-butane-1,4-dione 
• 120341-52-8 1,4-Bis-(2-hydroxy-4,6-dimethoxy-phenyl)-butane-1,4-dione 
• 621-23-8 1,2,3-trimethoxybenzene 
• 120341-55-1 1,4-Bis-(2-hydroxy-4,6-dimethoxy-phenyl)-2,3-bis-(4-methoxy-benzoyl)-butane-1,4-dione 

Relevant academic research and scientific papers

Synthesis and discovery of (I-3,II-3)-biacacetin as a novel non-zinc binding inhibitor of MMP-2 and MMP-9

Eleven biflavones (7a-b and 9a-i) were synthesised by a simple and efficient protocol and screened for MMP-2 and MMP-9 inhibitory activities. Amongst them, a natural product-like analog, (I-3,II-3)-biacacetin (9h) was found to be the most potent inhibitor

Total Synthesis of 3,3'-Biflavone

3,3'-Biflavones (7a) and (7b) have been successfully synthesized.