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Phenylahistin, a naturally occurring chemical compound derived from the marine strain of Streptomyces, is a potent inhibitor of tubulin polymerization. It demonstrates anticancer activity by disrupting microtubule dynamics and exerting strong cytotoxic effects on various cancer cell lines, including those resistant to other chemotherapeutic agents. As a promising lead compound for the development of novel anti-cancer drugs, Phenylahistin is the focus of ongoing research to further elucidate its mechanisms of action and potential therapeutic applications.

200815-37-8

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200815-37-8 Usage

Uses

Used in Pharmaceutical Industry:
Phenylahistin is used as an anticancer agent for its ability to inhibit tubulin polymerization and disrupt microtubule dynamics, leading to the suppression of cancer cell growth and proliferation. Its strong cytotoxic effects on a variety of cancer cell lines, including those resistant to other chemotherapeutic agents, make it a valuable candidate for the development of novel anti-cancer drugs.
Used in Cancer Research:
Phenylahistin is utilized as a research tool to further understand its mechanisms of action and potential therapeutic applications in cancer treatment. Ongoing studies aim to explore its interactions with tubulin and microtubules, as well as its potential synergistic effects when combined with other chemotherapeutic agents, to enhance its efficacy and overcome drug resistance in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 200815-37-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,0,8,1 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 200815-37:
(8*2)+(7*0)+(6*0)+(5*8)+(4*1)+(3*5)+(2*3)+(1*7)=88
88 % 10 = 8
So 200815-37-8 is a valid CAS Registry Number.

200815-37-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenylahistin

1.2 Other means of identification

Product number -
Other names (-)-(S)-phenylahistin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:200815-37-8 SDS

200815-37-8Upstream product

200815-37-8Downstream Products

200815-37-8Relevant academic research and scientific papers

Total synthesis of isoroquefortine E and phenylahistin

Shangguan, Ning,Joullié, Madeleine M.

supporting information; experimental part, p. 6755 - 6757 (2010/04/27)

Isoroquefortine E and phenylahistin were synthesized using the Horner-Wadsworth-Emmons reaction as the key step to build the dehydroamino acid moiety. The syntheses provided the materials for the biological studies of the roquefortine-phenylahistin molecu

METHODS OF PREPARATION OF DEHYDRO-DIKETOPIPERAZINES IN LIQUID PHASE OR OF SOLID SUPPORTED PHASE

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Page 10, (2008/06/13)

The preparation of any compound of the generic structure (I); wherein: R1 and R2 are substituents described in the main text. Cycl- is a group represented by either of the formulae (a) and (b); wherein: R3 to R8

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