200864-87-5Relevant academic research and scientific papers
Synthesis of 4-oxo- and 4-anti-formyl-8,10,12,13 -tetraoxapentacyclo[5.5.1.02,6.03,11.05,9]tridecanes
Wu, Hsien-Jen,Chern, Jyh-Haur
, p. 17653 - 17668 (2007/10/03)
The synthesis of 4-oxo- and 4-anti-formyl-8,10,12,13 -tetraoxapentacyclo[5.5.1.02,6.03,11.05,9]tridecanes has been accomplished. Ozonolysis of compounds 10a,b and 12a-c in dichloromethane at -78°C followed by reduction with dimethyl sulfide gave the title compounds, 4-oxo-tetraoxa-cages 11a,b and 14a-c, in moderate yields. Ozonolysis of the endo-syn isomers 15a,b and 18a,b under the same reaction conditions gave 4-anti-formyl-tetraoxa-cages 17a,b and 20a,b, respectively.
