201010-95-9 Usage
Uses
ER 27319 Maleate is a PLK-1 and Syk inhibitor.
Biological Activity
Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc ε RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- α production (IC 50 = 10 μ M) and other related signaling events.
Check Digit Verification of cas no
The CAS Registry Mumber 201010-95-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,0,1 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 201010-95:
(8*2)+(7*0)+(6*1)+(5*0)+(4*1)+(3*0)+(2*9)+(1*5)=49
49 % 10 = 9
So 201010-95-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H20N2O/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21/h3-4,6-9H,5,10-11,19H2,1-2H3
