201028-74-2Relevant academic research and scientific papers
Novel synthetic approach to pyrrolo[1,2-b]cinnolines
Abaev, Vladimir T.,Aksenov, Nicolai A.,Chalikidi, Petrakis N.,Demidov, Oleg P.,Gutnov, Andrey V.,Magkoev, Taimuraz T.,Plieva, Anastasia T.,Turiev, Anatolij M.
, (2020)
[Figure not available: see fulltext.] Straightforward method for the synthesis of pyrrolo[1,2-b]cinnolines starting from 2-nitrobenzaldehydes and 2-methylfurans has been elaborated. The key steps of the process are oxidative furan ring opening with diazon
Furyl(aryl)methanes and their derivatives. Part 21: Cinnnoline derivatives from 2-aminophenylbisfurylmethanes
Abaev, Vladimir T.,Gutnov, Andrey V.,Butin, Alexander V.,Zavodnik, Valerij E.
, p. 8933 - 8937 (2000)
(Z)-4-[4-(5-Methyl-2-furyl)-3-cinnolinyl]-3-buten-2-ones and (Z)-1-[4-(5-ethyl-2-furyl)-3-cinnolinyl]-1-penten-3-ones have been obtained from 2-aminoarylbisfurylmethanes under treatment with isoamyl nitrite/trimethylchlorosilane in dry acetonitrile. Intra
Synthesis of 2,4-difuryl-4H-3,1-benzothiazines via a furan ring migration reaction
Abaev, Vladimir T.,Tsiunchik, Fatima A.,Gutnov, Andrey V.,Butin, Alexander V.
, p. 475 - 481 (2008/09/19)
(Chemical Equation Presented) A new simple synthetic approach to 2,4-difuryl-4H-3,1-benzothiazines from 2-isothiocyanoaryldifurylmethanes in the presence of acidic catalyst is described. This rearrangement is a new example of furan ring migration reaction
Furan ring opening-indole ring closure: Synthesis of furo[2′, 3′:3,4]-cycloheota[1,2-b]indolium chlorides
Butin, Alexander V.,Smirnov, Sergey K.,Stroganova, Tatyana A.
, p. 623 - 628 (2007/10/03)
A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2-b] indolium chlorides is elaborated starting from 2-acetylaminoaryldifurylmethanes or 2-aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclization, intramolecular cyclization, and disproportionation. In this case the furan ring takes part in building up both pyrrole and seven-membered rings. The same salts can be obtained directly from 2-acetylaminobenzaldehydes and 2-methylfuran under similar conditions without isolation of corresponding 2-acetylaminoaryldifurylmethanes.
Polyfuryl(aryl)alkanes and their derivatives. 15. Products from the reduction of 2-nitroaryldifurylmethanes. Synthesis of indole derivatives
Butin,Stroganova,Abaev,Zavodnik
, p. 1393 - 1399 (2007/10/03)
The reduction of 2-nitrophenyldifurylmethane with SnCl2 leads to an indolenyl ketone as a result of intramolecular heterocycloaddition of the intermediately formed nitroso derivative. During the reduction of 2-nitroaryldifurylmethanes in the Zn
