201139-83-5

Upstream product

• 17158-47-3 7,7-dimethyl-7-silabicyclo[4.2.0]octa-1⁽⁶⁾,2,4-triene 
• 90-01-7 salicylic alcohol 
• 201140-05-8 2-tert-Butyl-4H-benzo[1,3]dioxine 
• 131472-85-0 3-tert-Butyl-1,1-dimethyl-3,4-dihydro-1H-benzo[c][1,2]oxasiline 

Relevant academic research and scientific papers

New homologation of 2-hydroxy and 2-mercapto benzylic alcohols

The reaction of benzo-1,3-dioxanes or benzo-1,3-oxathianes 1 [easily prepared from 2-hydroxy or 2-mercapto benzylic alcohols (3 or 4, respectively) and carbonyl compounds] with an excess of lithium and a catalytic amount of DTBB (4.5 mol %) in THF at room temperature or -78°C leads, alter hydrolysis with water, to the corresponding homobenzylic alcohols 2. Cyclisation of compounds 2 under acidic (85% H3PO4) or neutral (Ph3P/DIAD) conditions affords the expected heterocycles 5.

BASE INDUCED REACTION OF SILACYCLOBUTANE WITH ALDEHYDE OR EPOXIDE

The reaction of silacyclobutane with benzaldehyde in the presence of a catalytic amount of potassium t-butoxide gave six-membered cyclic silyl ether.Meanwhile, treatment of a mixture of silacyclobutane and epoxide with lithium diisopropylamide provided si