201140-08-1Relevant articles and documents
The catalytic asymmetric acetalization
Kim, Ji Hye,Coric, Ilija,Vellalath, Sreekumar,List, Benjamin
supporting information, p. 4474 - 4477 (2013/05/21)
In straitened circumstances: In an asymmetric version of the acid-catalyzed acetalization of aldehydes, a novel member of the chiral confined Bronsted acid family significantly outperformed previously established catalysts, providing cyclic acetals with e
New homologation of 2-hydroxy and 2-mercapto benzylic alcohols
Choudhury, Prabir K.,Almena, Juan,Foubelo, Francisco,Yus, Miguel
, p. 17373 - 17382 (2007/10/03)
The reaction of benzo-1,3-dioxanes or benzo-1,3-oxathianes 1 [easily prepared from 2-hydroxy or 2-mercapto benzylic alcohols (3 or 4, respectively) and carbonyl compounds] with an excess of lithium and a catalytic amount of DTBB (4.5 mol %) in THF at room temperature or -78°C leads, alter hydrolysis with water, to the corresponding homobenzylic alcohols 2. Cyclisation of compounds 2 under acidic (85% H3PO4) or neutral (Ph3P/DIAD) conditions affords the expected heterocycles 5.