201229-58-5

Basic information

• Product Name: N-(4-Amino-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-4-chloro-2-mercapto-5-methyl-benzenesulfonamide
• Synonyms: N-(4-Amino-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-4-chloro-2-mercapto-5-methyl-benzenesulfonamide
• CAS NO: 201229-58-5
• Molecular Weight: 416.912
• Mol File: 201229-58-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-Amino-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-4-chloro-2-mercapto-5-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Amino-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-4-chloro-2-mercapto-5-methyl-benzenesulfonamide(201229-58-5)
• EPA Substance Registry System: N-(4-Amino-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-4-chloro-2-mercapto-5-methyl-benzenesulfonamide(201229-58-5)

Safety Data

• Hazardous Substances Data: 201229-58-5(Hazardous Substances Data)

Upstream product

• 3731-59-7 moroxydine 

Relevant articles and documents

Synthesis of 4-chloro-2-mercapto-5-methyl-N-(2-amino-1, 3, 5-triazin-4-yl) benzenesulphonamide derivatives as potential anti-HIV agents

Several 4-chloro-2-mercapto-5-methyl-N-(2-amino-6-R1-1,3,5-triazin-4 -yl)benzenesuplhonamides [IVa-IVh] and disulphides (VI, VII], 2-[2-(2-amino-6-R1-1,3,5-triazin-4-ylaminosulphonyl)-5-chloro-4 -methylphenylthio]alkanoic acid [VII-XI] and 4-chloro-2-mercapto-5-methyl-N-(2-amino-7,8-diR3-benzo[4,5]imidazo[1,2 -a][1,3,5]triazin-4-yl)benzenesulphonamides [XIIa-XIIb], have been synthesized as potential anti-HIV agents. The structures of these compounds have been established on the basis of elemental analysis and spectral data (IR, 1H and 13C NMR). Preliminary screening data indicated that compounds (IVa,IVd-IVh, XIIa and XIIb] exhibit moderate or fairly high anti-HIV activity. Compounds [IVc and VII-XI] proved to be inactive in the anti-HIV test. The mentioned compound (XIIb] exhibits high activity against both HIV-1 (IIIB) and HIV-2 (ROD).