201283-56-9Relevant academic research and scientific papers
Expeditious synthesis of nicotianamine and 2′-deoxymugineic acid
Miyakoshi, Katsuhiro,Oshita, Jun,Kitahara, Takeshi
, p. 3355 - 3360 (2001)
A simple and efficient method of synthesizing nicotianamine 4 and 2′-deoxymugineic acid 3 was devised. We employed thioamide as an intermediate and the title compounds (4 and 3) were afforded via chemoselective reduction of the thioamides in 33% overall yield through 7 steps and 30% overall yield through 8 steps, respectively.
A novel synthetic approach towards phytosiderophores: Expeditious synthesis of nicotianamine and 2'-deoxymugineic acid
Klair, Sukhbinder S.,Mohan, Hindupur R.,Kitahara, Takeshi
, p. 89 - 92 (2007/10/03)
A short and a novel approach for synthesis of nicotianamine, 2'- deoxymugineic acid and related phytosiderophores has been achieved through peptide intermediates. Selective amide reduction in the presence of ester functionalities by conversion to thioamid
