201287-04-9Relevant academic research and scientific papers
Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3β
Shin, Dongkyu,Lee, Seung-Chul,Heo, Yong-Seok,Lee, Woon-Young,Cho, Yong-Soon,Kim, Yong Eun,Hyun, Young-Lan,Cho, Joong Myung,Lee, Yoon Sup,Ro, Seonggu
, p. 5686 - 5689 (2007)
A hydroxy functional group was introduced as the hydrogen bond donor and acceptor at the hinge region of protein kinase in order to develop novel ATP-competitive inhibitors. Several derivatives of 7-hydroxyl-1H-benzoimidazole were designed as inhibitors o
