201287-64-1

Upstream product

• 4254-02-8 cyclopentanecarbonitrile 
• 24812-90-6 methyl 3-amino-4-methoxybenzoate 
• 2840-26-8 3-amino-4-methoxybenzoic acid 

Relevant academic research and scientific papers

Structure-activity relationship of the 7-hydroxy benzimidazole analogs as glycogen synthase kinase 3β inhibitor

Design, synthesis and the GSK3β inhibitory activities of the 7-hydroxy benzimidazole analogs are described. The solid-phase synthetic route was also developed for preparation of the analogs consisting of the novel ATP competitive scaffold. In addition, th

2-substituted-4-methoxybenzimidazole-based PDE4 inhibitors

A new family of PDE4 inhibitors based on a benzimidazole framework is described. Several of these compounds are orally bioavailable and show efficacy in in vivo models of inflammatory disease.