2013-84-5Relevant academic research and scientific papers
KOtBu-Mediated Aerobic Transition-Metal-Free Regioselective β-Arylation of Indoles: Synthesis of β-(2-/4-Nitroaryl)-indoles
Kumar, Shailesh,Rathore, Vandana,Verma, Ajay,Prasad, Ch. Durga,Kumar, Amit,Yadav, Abhimanyu,Jana, Sadhan,Sattar, Moh,Meenakshi,Kumar, Sangit
, p. 82 - 85 (2014)
A KOtBu-mediated intermolecular oxidative C-C coupling of nitroarenes with indoles is presented in DMSO at room temperature in an open flask. By using this mild and economical methodology, syntheses of β-(2/4-nitroaryl)-indoles with sensitive f
KOtBu-mediated aerobic transition-metal-free regioselective β-arylation of indoles: Synthesis of β-(2-/4-Nitroaryl)-indoles
Kumar, Shailesh,Rathore, Vandana,Verma, Ajay,Prasad, Ch. Durga,Kumar, Amit,Yadav, Abhimanyu,Jana, Sadhan,Sattar, Moh.,Meenakshi,Kumar, Sangit
supporting information, p. 82 - 85 (2017/01/17)
A KOtBu-mediated intermolecular oxidative C-C coupling of nitroarenes with indoles is presented in DMSO at room temperature in an open flask. By using this mild and economical methodology, syntheses of β-(2/4-nitroaryl)-indoles with sensitive f
First heterogeneously palladium-catalysed fully selective C3-arylation of free NH-indoles
Cusati, Giuseppe,Djakovitch, Laurent
, p. 2499 - 2502 (2008/09/19)
A simple heterogeneously palladium-catalysed procedure for the selective C3-arylation of indoles is reported. Under relatively standard reaction conditions (Pd-catalyst, K2CO3, dioxane, reflux), using only 1 mol % [Pd(NH3)4]/NaY as the catalyst, indoles substituted or not at position 2 gave up to 92% conversion (i.e., 85% isolated yield) towards the expected C3-arylated indole.
Synthesis of 2-methylindole analogues and skatole dimers under Friedel-Crafts reaction conditions
Mahato, Shashi B.,Mandal, Nirup B.,Chattopadhyay, Sukanya,Luger, Peter,Weber, Manuela
, p. 12667 - 12676 (2007/10/02)
A one pot synthesis of 2-methylindole analogues and skatole dimers of biological interest using excess amounts of the substrates and the catalyst and higher temperature under Friedel-Crafts acylation conditions is reported. The products were defined by spectroscopic and single crystal X-ray analysis. Rationalization for the formation of the products has also been attempted.
