201350-64-3Relevant academic research and scientific papers
Ratiometric sensing lysosomal pH in inflammatory macrophages by a BODIPY-rhodamine dyad with restrained FRET
Yan, Yu,Zhang, Xiaodong,Zhang, Xinfu,Li, Ning,Man, Huizi,Chen, Lingcheng,Xiao, Yi
, p. 1091 - 1094 (2020)
Inflammation, as the pathophysiological response of body to harmful stimuli, leads to changes in cellular microenvironment. To research pH changes in lysosomes of macrophages during inflammation, we designed a FRET (F?rster resonance energy transfer) based probe, BDP-RhB. The probe showed good lysosome targeting ability, wide response range of pH from 8.0 to 4.0 with significant ratio (I582/I518) change from 0.6 to 3.4, and good reversibility and sustainability. By applying BDP-RhB, we found a decrease of lysosomal pH of macrophages during inflammation.
Acid-catalysed rearrangements between 3,4-dihydro-2H-1,5-benzooxazocine and -benzothiazocine and their macrocyclic (16-membered, 24-membered and 32-membered) oligomers
Hockless, David C. R.,Lindoy, Leonard F.,Swiegers, Gerhard F.,Bruce Wild
, p. 117 - 122 (2007/10/03)
Treatment of 2-(3-azidopropoxy)benzaldehyde with triphenylphosphine in diethyl ether, followed by sequestration of the products with nickel(II) thiocyanate and subsequent liberation from the complex with aqueous ammonia, produces the 16-membered dimer of
