201357-65-5Relevant academic research and scientific papers
Total synthesis of the putative structure of the marine alkaloid haliclorensin
Banwell,Bray,Edwards,Wong
, p. 1347 - 1350 (2007/10/03)
Compound 1, the structure of which has been assigned to the marine natural product haliclorensin, was prepared by an unambiguous synthetic pathway and subjected to spectroscopic analysis. The derived data do not match those reported for the natural produc
Amino Zinc Enolate Carbocyclization Reactions. New Access to Polysubstituted Piperidine Derivatives
Lorthiois, Edwige,Marek, Liane,Normant, Jean F.
, p. 566 - 574 (2007/10/03)
Various N-pent-4-enylglycine methyl esters have been submitted to carbocyclization of their zinc enolates onto the unactivated double bond. The cyclization to substituted pipecolic esters is highly stereoselective. In most cases, substitution of the pent-4-enyl moiety on various sites leads to a single isomer, hence a way to di-, tri-, tetra-, or pentasubstituted piperidines.
