201360-82-9 Usage
Description
Desogestrel delta-3 isoMer, also known as (5α,17α)-13-Ethyl-11-methylene-18,19-dinorpregn-3-en-20-yn-17-ol, is an impurity of Desogestrel, a progestogen with low androgenic potency. It is a synthetic steroid hormone that is used in various pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
Desogestrel delta-3 isoMer is used as an impurity in the production of Desogestrel, a progestogen with low androgenic potency. It is used in the development of contraceptive pills and hormone replacement therapies to regulate menstrual cycles and treat various gynecological conditions.
Desogestrel delta-3 isoMer is used as a quality control parameter in the manufacturing process of Desogestrel to ensure the purity and safety of the final product. The presence of this impurity is monitored and controlled to maintain the desired therapeutic effects and minimize potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 201360-82-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,3,6 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 201360-82:
(8*2)+(7*0)+(6*1)+(5*3)+(4*6)+(3*0)+(2*8)+(1*2)=79
79 % 10 = 9
So 201360-82-9 is a valid CAS Registry Number.
201360-82-9Relevant articles and documents
The remarkable influence of steroid A/B-ring junction on the Wittig olefination reaction of the 11-oxo group: Towards the synthesis of 5α- and 5β-oriented Δ3-isomers of desogestrel
Ring, Sven,Weber, Gisela,Hillisch, Alexander,Schwarz, Sigfrid
, p. 21 - 27 (1998)
The 5α- and 5β-oriented Δ3-double bond isomers 8, 9 of the widely used progestin desogestrel (7) were synthesized. Wittig olefination reaction of the 5α-intermediate 12 showed a dramatically reduced reaction rate compared with the olefination of the 5β-intermediate 13. Computational studies suggest that different energies of the intermediary 1,2- oxaphosphetanes may, at least partially, have been the reason for this phenomenon.
