201402-99-5

Upstream product

• 13603-62-8 1-(4-methylphenyl)-1,2-ethanediol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1258048-41-7 C₂₁H₂₄O₆S 
• 13107-39-6 2-(4-methylphenyl)oxirane 

Relevant academic research and scientific papers

Aralkylation of guanosine with para-substituted styrene oxides

To probe mechanisms of nucleoside aralkylation, product distributions and product stereochemistries were determined in reactions of optically active p-methyl- and p-bromostyrene oxide with guanosine. The proportion of 7-, N2-, and O6

Tandem SN2-Michael addition to vinylogous carbonates for the stereoselective construction of 2,3,3,5-tetrasubstituted tetrahydrofurans

A stereoselective method for the synthesis of substituted tetrahydrofuran derivatives employing a tandem alkylation-Michael addition sequence to vinylogous carbonates is developed. The method could be used to synthesize THFs bearing tertiary ethers. Further, the method is extended to the synthesis of adjacent bis-THFs.