201422-11-9Relevant academic research and scientific papers
Synthesis of the C1-C9 segment of bryostatin
Weiss, Jochen M.,Hoffmann
, p. 3913 - 3920 (1997)
The C1-C9 segment of bryostatin has been prepared in 11 steps in 21% overall yield.
Asymmetric synthesis of the northern half C1-C16 of the bryostatins
Vakalopoulos,Lampe,Hoffmann
, p. 929 - 932 (2007/10/03)
matrix presented Starting from 8-oxabicyclo[3.2.1]oct-6-en-3-one and racemic 2,2-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-one, the C1-C16 segment of the bryostatins has been synthesized in 30 steps and 9% overall yield (17 steps longest linear sequence). Fr
