201528-95-2

Upstream product

• 994-30-9 triethylsilyl chloride 
• 201528-94-1 C₃₇H₅₀O₁₂Si 
• 150541-99-4 7,13-O,O-Bis(triethylsilyl)baccatin III 

Relevant academic research and scientific papers

First synthesis and cytotoxic activity of novel docetaxel analogs modified at the C18-position

To investigate the effect of the C-18 position of docetaxel in its cytotoxic activity, 18-modified docetaxel analogs were synthesized for the first time from the 18-brominated baccatin derivatives. All of these analogs were found to be less active than docetaxel in cytotoxic activity against four test cell lines.