201595-65-5 Usage
Description
D-Fructose-13C6 is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine. It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate , which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet. Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity.
Uses
Isotope labelled D-Fructose (F792500), a monosaccharide that naturally occurs in large number of fruits and plants.
Check Digit Verification of cas no
The CAS Registry Mumber 201595-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,5,9 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 201595-65:
(8*2)+(7*0)+(6*1)+(5*5)+(4*9)+(3*5)+(2*6)+(1*5)=115
115 % 10 = 5
So 201595-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6?/m1/s1/i1+1,3+1,4+1,5+1,6+1
201595-65-5Relevant articles and documents
Integration of Enzymatic and Heterogeneous Catalysis for One-Pot Production of Fructose from Glucose
Sun, Jiankui,Li, Helong,Huang, Hongzhi,Wang, Bo,Xiao, Ling-Ping,Song, Guoyong
, p. 1157 - 1162 (2018/03/21)
The search for efficient routes for the production of fructose from biomass-derived glucose is of great interest and importance, as fructose is a highly attractive substrate in the conversion of cellulosic biomass into biofuels and chemicals. In this study, a one-pot, multistep procedure involving enzyme-catalyzed oxidation of glucose at C2 and Ni/C-catalyzed hydrogenation of d-glucosone at C1 selectively gives fructose in 77 % yield. Starting from upstream substrates such as α-cellulose and starch, fructose was also generated with similar efficiency and selectivity by the combination of enzymatic and heterogeneous catalysis. This method constitutes a new means of preparing fructose from biomass-derived substrates in an efficient fashion.
