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3,5,3',5'-Tetraiodo Thyroaldehyde, also known as Levothyroxine EP Impurity I or T4-Aldehyde (USP), is a chemical compound that serves as a thyroid hormone analogue and a Thyroxine (T425600) analogue. It is characterized by its beige solid appearance and possesses unique chemical properties that make it valuable in various applications.

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  • 2016-06-0 Structure
  • Basic information

    1. Product Name: 3,5,3',5'-Tetraiodo Thyroaldehyde
    2. Synonyms: 3,5,3',5'-Tetraiodo Thyroaldehyde;4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde;Levothyroxine Benzaldehyde IMpurity;Levothyroxine EP Impurity I
    3. CAS NO:2016-06-0
    4. Molecular Formula: C13H6I4O3
    5. Molecular Weight: 717.80282
    6. EINECS: N/A
    7. Product Categories: Aromatics;Drug Analogues;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 2016-06-0.mol
  • Chemical Properties

    1. Melting Point: 234 °C
    2. Boiling Point: 492.3±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 2.777±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator, Under Inert Atmosphere
    8. Solubility: Chloroform(Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
    9. PKA: 6.82±0.25(Predicted)
    10. CAS DataBase Reference: 3,5,3',5'-Tetraiodo Thyroaldehyde(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3,5,3',5'-Tetraiodo Thyroaldehyde(2016-06-0)
    12. EPA Substance Registry System: 3,5,3',5'-Tetraiodo Thyroaldehyde(2016-06-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2016-06-0(Hazardous Substances Data)

2016-06-0 Usage

Uses

Used in Pharmaceutical Industry:
3,5,3',5'-Tetraiodo Thyroaldehyde is used as a thyroid hormone analogue for the treatment of various thyroid-related conditions. As a synthetic version of the naturally occurring thyroid hormone, it helps regulate the body's metabolism and supports overall health.
Used in Research and Development:
In the field of research and development, 3,5,3',5'-Tetraiodo Thyroaldehyde is utilized as a Thyroxine analogue to study the effects and mechanisms of thyroid hormones. This understanding can lead to the development of new treatments and therapies for thyroid disorders and related health issues.
Used in Quality Control:
3,5,3',5'-Tetraiodo Thyroaldehyde is also used in the quality control of pharmaceutical products, specifically as an impurity reference substance. Its presence in the manufacturing process can help ensure the purity and efficacy of thyroid hormone medications, contributing to the overall safety and reliability of these drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 2016-06-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,1 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2016-06:
(6*2)+(5*0)+(4*1)+(3*6)+(2*0)+(1*6)=40
40 % 10 = 0
So 2016-06-0 is a valid CAS Registry Number.

2016-06-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde

1.2 Other means of identification

Product number -
Other names 3,5,3',5'-Tetraiodo Thyroaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2016-06-0 SDS

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