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Taltirelin hydrate is a synthetic peptide analog of thyrotropin-releasing hormone (TRH), acting as an agonist at the TRH receptor. It is a novel drug with potential for the treatment of spinocerebellar degeneration and other neurodegenerative diseases, showing promising results in improving motor function and reducing symptoms of ataxia through its mechanism of enhancing neurotransmitter release.

201677-75-0

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  • (4s)-n-[(2s)-1-[(2s)-2-carbamoylpyrrolidin-1-yl]-3-(1h-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carbo

    Cas No: 201677-75-0

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  • L-Prolinamide,N-[[(4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-,hydrate (1:4)

    Cas No: 201677-75-0

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201677-75-0 Usage

Uses

Used in Neurodegenerative Disease Treatment:
Taltirelin hydrate is used as a therapeutic agent for the treatment of spinocerebellar degeneration and other neurodegenerative diseases, for its potential to improve motor function and reduce ataxia symptoms. Its application is based on its ability to enhance the release of neurotransmitters such as dopamine and norepinephrine, contributing to its therapeutic effects.
Used in Clinical Trials:
Taltirelin hydrate is used as a subject of investigation in clinical trials, aimed at exploring its potential as a treatment for neurological disorders. The application is driven by its demonstrated efficacy in animal models and the need to assess its safety and effectiveness in human patients, with the goal of improving the quality of life for those affected by these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 201677-75-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,6,7 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 201677-75:
(8*2)+(7*0)+(6*1)+(5*6)+(4*7)+(3*7)+(2*7)+(1*5)=120
120 % 10 = 0
So 201677-75-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H23N7O5.4H2O/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26;;;;/h7-8,10-12H,2-6H2,1H3,(H2,18,26)(H,19,20)(H,21,27)(H,22,29);4*1H2/t10-,11-,12-;;;;/m0..../s1

201677-75-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide,tetrahydrate

1.2 Other means of identification

Product number -
Other names Taltirelin hydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:201677-75-0 SDS

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