20172-08-1Relevant academic research and scientific papers
Electrochemical Conversion of Phthaldianilides to Phthalazin-1,4-diones by Dehydrogenative N?N Bond Formation
Kehl, Anton,Gieshoff, Tile,Schollmeyer, Dieter,Waldvogel, Siegfried R.
supporting information, p. 590 - 593 (2017/12/26)
The electrochemical synthesis of 6-membered rings via anodic dianilide N?N coupling is challenging due to concurring benzoxazole co-formation. The rigidity of the a phthalic acid backbone allows a novel access to phthalazin-1,4-diones by N?N bond formation using anodically generated amidyl radicals. Since conventional synthetic routes to phthalazin-1,4-diones require the use of toxic N,N′-diarylhydrazines and generate reagent waste, a safer and more sustainable approach is required. Easy accessible starting materials, a broad scope of applicable functional groups, promising yields, and a very simple set-up elevate this sustainable method.
General method for quickly synthesizing bridge-linked bisamide, triamide and tetraamide derivatives through ultrasonic radiation method and application
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Paragraph 0066-0068, (2017/07/14)
The invention belongs to the technical field of organic synthesis, specifically discloses bridge-linked bisamide, triamide and tetraamide derivatives and a general method for ultrasonic radiation quick synthesis thereof, and also relates to the applicatio
